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By:

Abhijit Mulye

21 August 2024 at 11:29:11 am

High-stakes chess beneath the surface

BJP Candidates coming out after filing their nomination for the upcoming Legislative Council Polls from Vidhan Bhavan in Mumbai on Thursday. Pic: Bhushan Koyande Mumbai: Typically, when a ruling coalition enjoys a formidable and comfortable majority, elections to the Rajya Sabha and the State Legislative Council are quiet, predictable affairs. They are often viewed as mere formalities, rarely capturing the public imagination or dominating front-page headlines. Historically, these indirect...

High-stakes chess beneath the surface

BJP Candidates coming out after filing their nomination for the upcoming Legislative Council Polls from Vidhan Bhavan in Mumbai on Thursday. Pic: Bhushan Koyande Mumbai: Typically, when a ruling coalition enjoys a formidable and comfortable majority, elections to the Rajya Sabha and the State Legislative Council are quiet, predictable affairs. They are often viewed as mere formalities, rarely capturing the public imagination or dominating front-page headlines. Historically, these indirect elections only become newsworthy under specific conditions: either the ruling coalition is plagued by internal fissures, or the opposition is too fragmented to put up a united front. In Maharashtra, however, the political landscape remains highly volatile. Recently, the Rajya Sabha elections became the center of intense media scrutiny, and over the past week, the Legislative Council polls followed suit. Although all ten candidates—nine from the ruling alliance and one from the opposition Maha Vikas Aghadi (MVA)—are now set to be elected unopposed, the intricate backroom maneuvers that led to this truce kept the state’s political circles buzzing. Interestingly, the reason for this heightened news value can be traced to both a subtle tug-of-war within the ruling combine and a visibly weakened opposition. Shifting Strategy The maneuvering within the opposition ranks has been particularly telling. A major focal point of the election buildup was the anticipated candidacy of Shiv Sena (UBT) Chief Uddhav Thackeray. After generating considerable hype and speculation about a potential return to the legislature, Thackeray ultimately chose to withdraw from the electoral fray. This sudden pullback forced a rapid recalibration within the MVA. Initially, the Congress party had adopted an aggressive posture, declaring its intention to field a candidate if Thackeray decided against contesting. However, following closed-door deliberations with Shiv Sena (UBT) leadership, the Congress quietly backed down. Why the state Congress leadership so readily acquiesced to this sudden change in strategy, sacrificing a potential seat, remains a mystery and a subject of intense debate among political observers. On the other side of the aisle, the ruling Mahayuti coalition maximized this electoral opportunity to consolidate its political base, reward loyalists, and balance complex regional equations. The Nationalist Congress Party (NCP) strategically paved the way for the political rehabilitation of former Congress legislator Zishan Siddique by nominating him to the Legislative Council. This calculated move introduces a prominent new Muslim face for the party, likely intended to fill the leadership vacuum in Mumbai left by veteran leader Nawab Malik. Meanwhile, Chief Minister Eknath Shinde used his nominations to send a definitive message about the premium he places on loyalty. By securing another term for Dr. Neelam Gorhe, Shinde demonstrated that those who stood by his faction would be adequately rewarded. Furthermore, by bringing Vidarbha strongman Bachchu Kadu into the fold, Shinde has attempted to anchor his party’s future and expand its footprint in a region predominantly controlled by his senior alliance partner, the BJP. The Bharatiya Janata Party, playing its characteristic long game, meticulously ensured that its list of six candidates struck the perfect organizational, social, and political balance. Battle for LOP Despite these broader alliance strategies, the most consequential nomination in this electoral cycle is arguably that of Ambadas Danve. Barely six months after completing his tenure in the Upper House and stepping down from the prestigious post of Leader of the Opposition in the Legislative Council, Danve has been nominated once again by the Shiv Sena (UBT). With his return to the house, there is a strong possibility that he will reclaim his former post. This specific development highlights a much deeper crisis within the Congress. Following Danve’s brief retirement, the Congress had naturally emerged as the largest opposition party in the Upper House. This mathematical advantage theoretically paved the way for their Kolhapur strongman, Satej “Banti” Patil, to lay claim to the Leader of the Opposition’s chair. However, the sudden defection of Congress MLC Pradnya Satav, who switched loyalties to the BJP, severely dented the party’s numbers. Her departure brought the Congress’s strength in the house just below that of the Shiv Sena (UBT). Stripped of its numerical superiority overnight, the Congress was relegated to being a mute spectator, unable to assert its rightful claim. Internal Dissent This series of tactical defeats has triggered palpable frustration within the Congress’s state unit. One senior Congress leader, speaking on the condition of anonymity, expressed deep disappointment with the state leadership’s inability to protect the party’s interests. “Everyone has personal political ambitions, but leaders must learn the ways to collectively move ahead and strategize,” the leader remarked, attributing the party’s current stagnation in Maharashtra to this lack of cohesive vision. In short, these Legislative Council elections have delivered one message loud and clear: even when everything appears calm and stable on the surface, the relentless machinery of politics continues to churn behind the scenes. No political player in Maharashtra can afford to rest assured or sit idle under the illusion that there are no major state elections until 2029.

AI in Sperm Sorting: An Unbiased Decision for A Better Outcome

Artificial Intelligence or AI is revolutionising fertility treatments of the future. The inclusion of AI enhances the accuracy, efficiency, and objectivity of sperm selection, hence potentially improving fertility outcomes by leaps and bounds. Traditionally, sperm sorting through manual methods is subjective to judgments. Processes like centrifugation and swim-up methods are used to separate sperm based on motility and morphology. Although they are effective, they have their limitations, leading to human errors that affect the success rates of fertility treatment. For instance, studies have shown that traditional sperm sorting techniques can have variability in success rates, with reported live birth rates ranging between 15 per cent to 25 per cent per cycle depending on the method and quality of sperm. Hence the introduction of AI helps in maintaining consistency in evaluations of sperm, using the same data set for every sample which leads to better judgments.


Automation and Standardisation- Automation of sperm selection and also introduction of AI in the process have improved the results in ART. AI-assisted sperm selection improves the accuracy in choosing high-quality sperm for fertilisation purposes, and also, pregnancy and live birth rates might be improved. Technologies like Intracytoplasmic Morphologically Selected Sperm Injection along with AI ensure the chances of pregnancies increase by about 10-20 per cent compared to the standard procedures. AI and Automation will decrease time taken to analyze sperm and increase opportunities to select better sperm with DNA integrity for better development and higher success rates in embryo selection. These processes ensure that the sperm selection process follows consistent criteria, reducing variability in outcomes caused by human error.


Analysing Complex Data for Better Outcomes- AI plays a crucial in improving IVF outcomes by analysing complex data and providing tailored recommendations. AI-driven tools and models such as those on SpOvum.ai point towards an opportunity to optimise ovarian stimulation decisions by assessing patient characteristics and follicle growth patterns. A study revealed that the use of AI in IVF improved egg yield and reduced medication costs. AI enables fertility specialists to make data-driven choices, improving overall IVF success rates and streamlining treatment processes.


Reducing Human Error- AI models can continuously learn and refine their performance by being trained on newer data. This adaptability ensures the technology remains unbiased and up-to-date with the latest scientific insights into sperm quality and fertility success rates. Studies have shown that AI-driven sperm sorting can decrease human-related errors by up to 25 per cent, improving sperm selection quality in terms of morphology and motility.


Reduction of Sperm Damage- The new AI-driven sperm sorting techniques also include microfluidic systems that are known to exhibit several advantages over the most commonly used conventional method, which is centrifugation. Traditional centrifugation methods, such as density gradient centrifugation, also cause severe oxidative stress and DNA fragmentation of the sperm because of the very high mechanical forces involved. The AI-infused microfluidic sorting minimises this damage significantly by involving gentler processes that mimic the natural pathway of sperm selection. The studies show that the process of microfluidic sorting decreases DNA fragmentation in sperm, which gives improved opportunities for success for IVF. For example, DNA fragmentation is 20 percent lower in sperm sorted using microfluidic processes than in traditional processing methods.


AI is bound to play an increasingly definitive role in fertility treatments, which will improve the outcomes for couples experiencing infertility.


(The author is a Co-Founder & CEO at SpOvum® Technologies. Views personal.)

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